Redefining expectations of long- Term survival after the fontan procedure twenty-five years of follow-up from the entire population of Australia and New Zealand

Y D'udekem; AJ Iyengar; JC Galati; V Forsdick; RG Weintraub; GR Wheaton; A Bullock; RN Justo; LE Grigg; GF Sholler; S Hope; DJ Radford; TL Gentles; DS Celermajer; DS Winlaw

Journal article

Redefining expectations of long- Term survival after the fontan procedure twenty-five years of follow-up from the entire population of Australia and New Zealand

Y D'udekem, AJ Iyengar, JC Galati, V Forsdick, RG Weintraub, GR Wheaton, A Bullock, RN Justo, LE Grigg, GF Sholler, S Hope, DJ Radford, TL Gentles, DS Celermajer, DS Winlaw

Circulation | LIPPINCOTT WILLIAMS & WILKINS | Published : 2014

DOI: 10.1161/CIRCULATIONAHA.113.007764

Abstract

Background-The life expectancy of patients undergoing a Fontan procedure is unknown. Methods and Results-Follow-up of all 1006 survivors of the 1089 patients who underwent a Fontan procedure in Australia and New Zealand was obtained from a binational population-based registry including all pediatric and adult cardiac centers. There were 203 atriopulmonary connections (AP; 1975-1995), 271 lateral tunnels (1988-2006), and 532 extracardiac conduits (1997-2010). The proportion with hypoplastic left heart syndrome increased from 1/173 (1%) before 1990 to 80/500 (16%) after 2000. Survival at 10 years was 89% (84%-93%) for AP and 97% (95% confidence interval [CI], 94%-99%) for lateral tunnels and e..

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University of Melbourne Researchers

Yves D'Udekem D'Acoz Author

Robert Weintraub Author

Related Projects (1)

IMPROVING FUNCTIONAL OUTCOMES AFTER FONTAN SURGERY BY A CROSS-SECTIONAL STUDY OF THE OUTCOMES FOLLOWING VARIATION IN PRACTICE IN AUSTRALIA AND NEW ZEALAND: FOCUS ON ANTICOAGULATION AND CARDIAC SHUNTING BY THE FENESTRATION

The Fontan procedure is the last of a series of life-saving operations offered to children born with only one pumping chamber in their heart..

Grants

Awarded by Royal Australasian College of Surgeons

Funding Acknowledgements

Dr d'Udekem is a Career Development Fellow of The National Heart Foundation of Australia (CR 10M 5339). The Australia and New Zealand Fontan Registry is funded by grants from the National Heart and Medical Research Council (NHMRC; Project Grants 1012241, 1047923, 1065794), HeartKids, and the Australian and New Zealand ( ANZ) Bank Trustees. Dr Iyengar has received postgraduate awards from the Royal Australasian College of Surgeons (Catherine Marie Enright Kelly and Eric Bishop Scholarships) and the NHMRC and The National Heart Foundation of Australia (1038802). The authors acknowledge support provided to the Murdoch Childrens Research Institute by the Victorian Government's Operational Infrastructure Support Program.